GBF1

Also known as ARF1GEF, golgi brefeldin A resistant guanine nucleotide exchange factor 1, CMT2GG

Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to GBF1, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 10.

Vinony links it to 5 Wikipedia language editions.

Gene data

GBF1

Name: golgi brefeldin A resistant guanine nucleotide exchange factor 1
Type: protein-coding
Position: 102,245,371–102,382,899 (+)
Aliases: ARF1GEF, CMT2GG, CMTDI2, CMTDIA
Ensembl: ENSG00000107862
RefSeq RNA: NM_001199378.2, NM_001199379.2, NM_001377137.1, NM_001377138.1, NM_001377139.1
RefSeq protein: NP_001186307.1, NP_001186308.1, NP_001364066.1, NP_001364067.1, NP_001364068.1

This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010].