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GeneQ18045558· pop 5· linked from 352 articles

Also known as GDNF family receptor alpha 4

GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.

Gene data

GFRA4
Name
GDNF family receptor alpha 4
Type
protein-coding

The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Wikidata facts

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HomoloGene ID
10565
genomic end
3644046
genomic start
3659248
cytogenetic location
20p13
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GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.

==See also== GFRα

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