glibornuride

Also known as Ro-64563, Glutril, Glibornurid, Glibornurida, Glibornuridum

Glibornuride (INN) is an anti-diabetic drug from the group of sulfonylureas. It is manufactured by MEDA Pharma and sold in Switzerland under the brand name Glutril.

Chemical data

Formula: C18H26N2O4S
Molecular weight: 366.5 g/mol
IUPAC name: 1-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]-3-(4-methylphenyl)sulfonylurea
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)N[C@H]2[C@H]3CC[C@@]([C@H]2O)(C3(C)C)C
InChIKey: RMTYNAPTNBJHQI-LLDVTBCESA-N
XLogP: 3.2
Polar surface area: 104 Å²
H-bond donors: 3
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
Indications: diabetes mellitus

via ChEMBL · EBI

Research

87 papers

via PubMed

Wikidata facts

Mass: 366.161328
Has use: medication

Show 6 more facts

chemical formula: C₁₈H₂₆N₂O₄S
defined daily dose: 38
canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2C3CCC(C2O)(C3(C)C)C
isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)N[C@H]2[C@H]3CC[C@@]([C@H]2O)(C3(C)C)C
subject has role: anti-diabetic medication
Commons category: Glibornuride

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

Synthesis
References

{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444003955 | ImageFile = Glibornuride.svg | ImageClass = skin-invert-image | ImageSize = 250 | IUPACName = N-{[(1R,2R,3S,4S)-2-Hydroxybornan-3-yl]carbamoyl}-4-methylbenzene-1-sulfonamide | SystematicName = N-{[(1S,2S,3R,4R)-3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]carbamoyl}-4-methylbenzene-1-sulfonamide | OtherNames =

| Section1 =

Excerpted from Wikipedia’s “glibornuride” article, available under the CC BY-SA 4.0 licence.

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