glibornuride

Also known as Ro-64563, Glutril, Glibornurid, Glibornurida, Glibornuridum

Glibornuride (INN) is an anti-diabetic drug from the group of sulfonylureas. It is manufactured by MEDA Pharma and sold in Switzerland under the brand name Glutril.

In the Vinony graph

Within Vinony's link graph, glibornuride is referenced by 445 other articles, and connects out to metformin, valproic acid and anti-diabetic medication.

It sits within the topics Benzenesulfonylureas, Chembox image size set and ECHA InfoCard ID from Wikidata.

Its subject is documented across 9 Wikipedia language editions.

Chemical data

Formula: C18H26N2O4S
Molecular weight: 366.5 g/mol
IUPAC name: 1-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]-3-(4-methylphenyl)sulfonylurea
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)N[C@H]2[C@H]3CC[C@@]([C@H]2O)(C3(C)C)C
InChIKey: RMTYNAPTNBJHQI-LLDVTBCESA-N
XLogP: 3.2
Polar surface area: 104 Å²
H-bond donors: 3
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
Indications: diabetes mellitus

via ChEMBL · EBI

Research

87 papers

via PubMed

Wikidata facts

Mass: 366.161328
Has use: medication

Show 6 more facts

chemical formula: C₁₈H₂₆N₂O₄S
defined daily dose: 38
canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2C3CCC(C2O)(C3(C)C)C
isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)N[C@H]2[C@H]3CC[C@@]([C@H]2O)(C3(C)C)C
subject has role: anti-diabetic medication
Commons category: Glibornuride

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

Synthesis
References

{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444003955 | ImageFile = Glibornuride.svg | ImageClass = skin-invert-image | ImageSize = 250 | IUPACName = N-{[(1R,2R,3S,4S)-2-Hydroxybornan-3-yl]carbamoyl}-4-methylbenzene-1-sulfonamide | SystematicName = N-{[(1S,2S,3R,4R)-3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]carbamoyl}-4-methylbenzene-1-sulfonamide | OtherNames =

| Section1 =

Excerpted from Wikipedia’s “glibornuride” article, available under the CC BY-SA 4.0 licence.