ibutilide
Sign in to saveIbutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells. Because of its Class III antiarrhythmic activity, there should not be concomitant administration of Class Ia and Class III agents.
Chemical data
- Formula
- C20H36N2O3S
- Molecular weight
- 384.6 g/mol
- IUPAC name
- N-[4-[4-[ethyl(heptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide
via PubChem
Article
10 sectionsContents
- Mechanism of action
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Excretion
- Adverse effects and contraindications
- Patient Information
- See also
- References
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| tradename = Corvert | Drugs.com = | MedlinePlus = a601248 | pregnancy_AU = | pregnancy_US = | pregnancy_category = C | legal_AU = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intravenous