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EntityQ17630273· pop 16· linked from 81 articles

Idarucizumab

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Also known as Praxbind

Idarucizumab, sold under the brand name Praxbind, is a monoclonal antibody used as a reversal agent for dabigatran.

Key facts

Drug.pregnancy_AU
B2
Drug.type
mab
Drug.mab_type
Fab
Drug.source
zu/o
Drug.target
Dabigatran
Drug.tradename
Praxbind
Drug.DailyMedID
Idarucizumab
Drug.routes_of_administration
Intravenous
Drug.ATC_prefix
V03
Drug.ATC_suffix
AB37
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_UK
POM
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.CAS_number
1362509-93-0
Drug.IUPHAR_ligand
8298
Drug.DrugBank
DB09264

via Wikipedia infobox

Wikidata facts

Has use
medication
Show 4 more facts
World Health Organisation international non-proprietary name
idarucizumab
stylized name
idaruCIZUmab
has characteristic
biopharmaceutical
subject has role
monoclonal antibody
Sources (5)

via Wikidata · CC0

~2 min read

Encyclopedic overview

7 sections
Contents
  • Mechanism of action
  • Medical uses
  • Adverse effects
  • Pregnancy
  • Society and culture
  • Names
  • References

Idarucizumab, sold under the brand name Praxbind, is a monoclonal antibody used as a reversal agent for dabigatran.

Idarucizumab was developed by Boehringer Ingelheim. One study sponsored by the manufacturer found that idarucizumab effectively reversed anticoagulation caused by dabigatran within minutes.

Excerpted from Wikipedia’s “Idarucizumab” article, available under the CC BY-SA 4.0 licence.