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inogatran

Structure via PubChem · Public domain (PubChem)

EntityQ6036513· pop 5· linked from 114 articles

Inogatran (INN) is a low molecular weight peptidomimetic thrombin inhibitor. Inogatran was developed for the potential treatment of arterial and venous thrombotic diseases.

Chemical data

Formula
C21H38N6O4
Molecular weight
438.6 g/mol
IUPAC name
2-[[(2R)-3-cyclohexyl-1-[(2S)-2-[3-(diaminomethylideneamino)propylcarbamoyl]piperidin-1-yl]-1-oxopropan-2-yl]amino]acetic acid
SMILES
C1CCC(CC1)C[C@H](C(=O)N2CCCC[C@H]2C(=O)NCCCN=C(N)N)NCC(=O)O
InChIKey
CDPROXZBMHOBTQ-SJORKVTESA-N
XLogP
-1.2
Polar surface area
163 Ų
H-bond donors
5
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
438.295
Show 4 more facts
canonical SMILES
C1CCC(CC1)CC(C(=O)N2CCCCC2C(=O)NCCCN=C(N)N)NCC(=O)O
isomeric SMILES
C1CCC(CC1)C[C@H](C(=O)N2CCCC[C@H]2C(=O)NCCCN=C(N)N)NCC(=O)O
chemical formula
C₂₁H₃₈N₆O₄
Commons category
Inogatran
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

{{chembox | ImageFile = Inogatran.svg | ImageClass = skin-invert-image | ImageSize = 275px | ImageAlt = | IUPACName = 2-{[(2R)-1-[(2S)-2-[(4-Carbamimidamidopropyl)carbamoyl]piperidin-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino}acetic acid | OtherNames = N-[(1R)-2-Cyclohexyl-1-[[(2S)-2-[(3-guanidinopropyl)carbamoyl]piperidino]carbonyl]ethyl]glycine

| Section1 =

Excerpted from Wikipedia’s “inogatran” article, available under the CC BY-SA 4.0 licence.

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