Structure via PubChem · Public domain (PubChem)
phenindione
Sign in to saveAlso known as Dindevan®, phenylindanedione, 2-Phenyl-1,3-indandione, PID, 2-phenyl-1,3-diketohydrindene, 2-phenyl-1,3(2H)-Indenedione, Phenindion, Phenindionum
Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Chemical data
- Formula
- C15H10O2
- Molecular weight
- 222.24 g/mol
- IUPAC name
- 2-phenylindene-1,3-dione
- SMILES
- C1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O
- InChIKey
- NFBAXHOPROOJAW-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 34.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral
- Indications
- Recurrent thrombophlebitis, pregnancy
via ChEMBL · EBI
Research
926 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 222.06808
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₅H₁₀O₂
- canonical SMILES
- C1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O
- defined daily dose
- 0.1
- World Health Organisation international non-proprietary name
- phenindione
- subject has role
- anticoagulant
- Commons category
- Phenindione
- significant drug interaction
- (S)-duloxetine
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Phenindione was introduced in the early 1950s. It acts similar to warfarin, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred.
Excerpted from Wikipedia’s “phenindione” article, available under the CC BY-SA 4.0 licence.