Structure via PubChem · Public domain (PubChem)
tioclomarol
Sign in to saveAlso known as Apegmone, 3-[3-(4-chlorophenyl)-1-(5-chlorothiophen-2-yl)-3-hydroxypropyl]-4-hydroxychromen-2-one
Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation drug, used as a rodenticide that is effective for the control of rodents that are resistant to this class of drugs.
Chemical data
- Formula
- C22H16Cl2O4S
- Molecular weight
- 447.3 g/mol
- IUPAC name
- 3-[3-(4-chlorophenyl)-1-(5-chlorothiophen-2-yl)-3-hydroxypropyl]-2-hydroxychromen-4-one
- SMILES
- C1=CC=C2C(=C1)C(=O)C(=C(O2)O)C(CC(C3=CC=C(C=C3)Cl)O)C4=CC=C(S4)Cl
- InChIKey
- XGZCHPQWRLBXDZ-UHFFFAOYSA-N
- XLogP
- 5.6
- Polar surface area
- 95 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Recurrent thrombophlebitis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 446.0146353519999
- Has use
- medication
Show 2 more facts
- chemical formula
- C₂₂H₁₆Cl₂SO₄
- canonical SMILES
- C1=CC=C2C(=C1)C(=C(C(=O)O2)C(CC(C3=CC=C(C=C3)Cl)O)C4=CC=C(S4)Cl)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation drug, used as a rodenticide that is effective for the control of rodents that are resistant to this class of drugs.
==References==
Excerpted from Wikipedia’s “tioclomarol” article, available under the CC BY-SA 4.0 licence.