KLHDC3
Sign in to saveAlso known as PEAS, dJ20C7.3, kelch domain containing 3
Kelch domain-containing protein 3 is a protein that in humans is encoded by the KLHDC3 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to KLHDC3, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
Vinony files it under Genes on human chromosome 6 and Kelch proteins.
Vinony links it to 6 Wikipedia language editions.
Gene data
KLHDC3- Name
- kelch domain containing 3
- Type
- protein-coding
- Position
- 43,014,103–43,021,314 (+)
- Aliases
- PEAS, dJ20C7.3
- Ensembl
- ENSG00000124702
- RefSeq RNA
- NM_001242872.1, NM_057161.4, NR_040101.2, XM_047418163.1, XM_047418164.1
- RefSeq protein
- NP_476502.1, XP_047274119.1, XP_047274120.1, XP_054210163.1, XP_054210164.1
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination. [provided by RefSeq, Jun 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
kelch domain containing 3
- Symbol
- KLHDC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:43,014,103-43,021,314
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 14290
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/116138
- genomic end
- 42989036
- genomic start
- 42981951
- chromosome
- human chromosome 6
- cytogenetic location
- 6p21.1
- expressed in
- nucleus accumbens
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Kelch domain-containing protein 3 is a protein that in humans is encoded by the KLHDC3 gene.
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. This gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasm and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination.
Excerpted from Wikipedia’s “KLHDC3” article, available under the CC BY-SA 4.0 licence.