Structure via PubChem · Public domain (PubChem)
الپی-۱۲
Sign in to saveAlso known as compound 21 [PMID 17649988]
LP-12 is a drug which acts as a potent agonist at the 5HT7 serotonin receptor, with very high selectivity over other tested receptor subtypes such as the serotonin 5-HT1A and 5-HT2A, and the dopamine D2 receptor. It has been used to research the involvement of the 5-HT7 receptor in as yet poorly understood processes such as allodynia and hyperalgesia.
Chemical data
- Formula
- C32H39N3O
- Molecular weight
- 481.7 g/mol
- IUPAC name
- 6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
- SMILES
- C1CC(C2=CC=CC=C2C1)NC(=O)CCCCCN3CCN(CC3)C4=CC=CC=C4C5=CC=CC=C5
- InChIKey
- NMZIDFFHGCRAJV-UHFFFAOYSA-N
- XLogP
- 6.1
- Polar surface area
- 35.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 481.309313
Show 2 more facts
- chemical formula
- C₃₂H₃₉N₃O
- canonical SMILES
- C1CC(C2=CC=CC=C2C1)NC(=O)CCCCCN3CCN(CC3)C4=CC=CC=C4C5=CC=CC=C5
Sources (1)
via Wikidata · CC0