Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C19H20Br2N6O4S
- Molecular weight
- 588.3 g/mol
- IUPAC name
- 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
- SMILES
- CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
- InChIKey
- JGCMEBMXRHSZKX-UHFFFAOYSA-N
- XLogP
- 3.7
- Polar surface area
- 137 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2010
- Admin. routes
- oral
- Indications
- pulmonary arterial hypertension, idiopathic pulmonary fibrosis, systemic scleroderma, glioblastoma multiforme
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 585.9633483200003
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₉H₂₀Br₂N₆O₄S
- canonical SMILES
- CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
- World Health Organisation international non-proprietary name
- macitentan
- defined daily dose
- 10
- medical condition treated
- pulmonary hypertension
- Commons category
- Macitentan
- legal status (medicine)
- boxed warning
Sources (7)
via Wikidata · CC0
Article · Français
Le macitentan est un inhibiteur des récepteurs de l'endothéline utilisée comme traitement de l'hypertension artérielle pulmonaire. Il s'agit d'une modification du bosentan, autre médicament de la même classe.
Abstract from DBpedia / Wikipedia · CC BY-SA
Gallery (2)
Available in 11 languages
via Wikidata sitelinks · CC0