Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Within Vinony's link graph, Macitentan is referenced by 159 other articles, and connects out to digital object identifier, chemical formula and integral.
It sits within the topics 4-Bromophenyl compounds, Bromoarenes and Drugs developed by Johnson & Johnson.
Its subject is documented across 11 Wikipedia language editions.
Chemical data
- Formula
- C19H20Br2N6O4S
- Molecular weight
- 588.3 g/mol
- IUPAC name
- 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
- SMILES
- CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
- InChIKey
- JGCMEBMXRHSZKX-UHFFFAOYSA-N
- XLogP
- 3.7
- Polar surface area
- 137 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2010
- Admin. routes
- oral
- Indications
- pulmonary arterial hypertension, idiopathic pulmonary fibrosis, systemic scleroderma, glioblastoma multiforme
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 585.9633483200003
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₉H₂₀Br₂N₆O₄S
- canonical SMILES
- CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
- World Health Organisation international non-proprietary name
- macitentan
- defined daily dose
- 10
- medical condition treated
- pulmonary hypertension
- Commons category
- Macitentan
- legal status (medicine)
- boxed warning
Sources (7)
via Wikidata · CC0
Gallery (2)
Available in 11 languages
via Wikidata sitelinks · CC0
Connections
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chemical formula
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sildenafil
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molar mass
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excretion
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diuretic
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PubChem
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Anatomical Therapeutic Chemical Classification System
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pharmacokinetics
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MedlinePlus
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simplified molecular input line entry specification
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rac-warfarin
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digoxin
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rifampicin
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pulmonary hypertension
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