melatonina

Also known as MLT, N-[2-(5-methoxyindol-3-yl)ethyl]acetamide, 5-methoxy-N-acetyltryptamine, Melovine, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} Acetamide, N-(2-(5-Methoxyindol-3-yl)ethyl)-Acetamide, N-Acetyl-5-methoxy-tryptamine, N-[2-(5-Methoxyindol-3-yl)ethyl]-Acetamide

ormone prodotto dalla ghiandola pineale (o epifisi), ghiandola posta alla base del cervello

OverviewAI-generated

Melatonin is a chemical compound with the formula C₁₃H₁₆N₂O₂. Its IUPAC name is N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide. The substance has a mass of 232.121 and a weight of 232.28. It carries a charge of 0 and features two hydrogen bond donors and two hydrogen bond acceptors. The calculated xlogp value is 0.8, while the topological polar surface area (TPSA) is 54.1.

The defined daily dose for melatonin is 2.0. The compound is associated with a PubMed query count of 37218. It is referenced by 1,555 other encyclopedia articles.

Synthesized by Vinony from 20 facts across 4 sources: Wikidata, PubChem, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

In the Vinony graph

Vinony's link graph records 1,555 inbound references to melatonina, and connects out to tryptamines, controlled release and serotonin.

Vinony files it under 5-Methoxytryptamines, ECHA InfoCard ID from Wikidata and Melatonin.

Vinony links it to 72 Wikipedia language editions.

Chemical data

Formula: C13H16N2O2
Molecular weight: 232.28 g/mol
IUPAC name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
InChIKey: DRLFMBDRBRZALE-UHFFFAOYSA-N
XLogP: 0.8
Polar surface area: 54.1 Å²
H-bond donors: 2
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 2007
Admin. routes: oral
Indications: sunburn, substance withdrawal syndrome, aortic aneurysm, metabolic syndrome

via ChEMBL · EBI

Research

37,218 papers

via PubMed

Wikidata facts

Subclass of: hormone
Has part: carbon
Mass: 232.121
Has use: medication

Show 11 more facts

medical condition treated: jet lag
Commons category: Melatonin
found in taxon: Trigonella foenum-graecum
chemical formula: C₁₃H₁₆N₂O₂
topic's main category: Category:Melatonin
canonical SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
isomeric SMILES: C/C(=N\CCC1=CNC2=C1C=C(C=C2)OC)/O
defined daily dose: 2.0
subject has role: primary metabolite
WordLift URL: data.medicalrecords.com/medicalrecords/healthwise/melatonin
different from: melanin

Sources (11)

via Wikidata · CC0

Article · Italiano

La melatonina (chimicamente N-acetil-5-metossitriptammina) è un ormone prodotto dalla ghiandola pineale (o epifisi), ghiandola posta alla base del cervello. Agisce sull'ipotalamo e ha la funzione di regolare il ciclo sonno-veglia. Oltre che negli esseri umani, essa è prodotta anche da altre specie di animali, piante (fitomelatonina) e microorganismi.

Abstract from DBpedia / Wikipedia · CC BY-SA