methazolamide
Sign in to saveAlso known as methenamide
Methazolamide (trade name Neptazane) is a potent carbonic anhydrase inhibitor. It is indicated in the treatment of increased intraocular pressure (IOP) in chronic open-angle glaucoma and secondary glaucoma. Also it is used preoperatively in acute angle-closure (narrow-angle) glaucoma where lowering the IOP is desired before surgery.
Research
520 papers- Methazolamide.2006
- Methazolamide in high-altitude illnesses.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2020
- Imatinib and methazolamide ameliorate COVID-19-induced metabolic complications via elevating ACE2 enzymatic activity and inhibiting viral entry.Cell metabolism · 2022
- The Impact of Acetazolamide and Methazolamide on Exercise Performance in Normoxia and Hypoxia.High altitude medicine & biology · 2023
- Association between HLA-B*5901 and methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis.The pharmacogenomics journal · 2019
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 236.003782
- Has use
- medication
Show 8 more facts
- chemical formula
- C₅H₈N₄O₃S₂
- canonical SMILES
- CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C
- defined daily dose
- 0.2
- NCI Thesaurus ID
- C61318
- subject has role
- diuretic
- different from
- methimazole
- stylized name
- methazolAMIDE
- Commons category
- Methazolamide
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- References
- Further reading
Methazolamide (trade name Neptazane) is a potent carbonic anhydrase inhibitor. It is indicated in the treatment of increased intraocular pressure (IOP) in chronic open-angle glaucoma and secondary glaucoma. Also it is used preoperatively in acute angle-closure (narrow-angle) glaucoma where lowering the IOP is desired before surgery.
This drug has displayed teratogenic effects in rats. Compared to another drug in the same class, acetazolamide, methazolamide requires a lower dose when administered to patients.
Excerpted from Wikipedia’s “methazolamide” article, available under the CC BY-SA 4.0 licence.