Structure via PubChem · Public domain (PubChem)
carteolol
Sign in to saveAlso known as ABBOTT-43326, Cartrol®, Ocupress®, OPC-1085, Carteololum
Carteolol is a non-selective beta blocker used to treat glaucoma. It is administered in the form of eye drops.
Chemical data
- Formula
- C16H24N2O3
- Molecular weight
- 292.37 g/mol
- IUPAC name
- 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one
- SMILES
- CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O
- InChIKey
- LWAFSWPYPHEXKX-UHFFFAOYSA-N
- XLogP
- 1
- Polar surface area
- 70.6 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1988
- Admin. routes
- oral, topical
- Indications
- cardiovascular disease, glaucoma
via ChEMBL · EBI
Research
504 papers- Carteolol.2006
- Ocular carteolol: a review of its use in the management of glaucoma and ocular hypertension.Drugs & aging · 2007
- Ocular carteolol. A review of its pharmacological properties, and therapeutic use in glaucoma and ocular hypertension.Drugs & aging · 1992
- Carteolol triggers senescence via activation of β-arrestin-ERK-NOX4-ROS pathway in human corneal endothelial cells in vitro.Chemico-biological interactions · 2023
- 0.01% atropine combined with carteolol hydrochloride can inhibit the scleral remodeling in guinea pigs with form-deprivation myopia.Scientific reports · 2025
via PubMed
Wikidata facts
- Mass
- 292.178693
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₆H₂₄N₂O₃
- medical condition treated
- arterial hypertension
- canonical SMILES
- CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O
- World Health Organisation international non-proprietary name
- carteolol
- Commons category
- Carteolol
- defined daily dose
- 10
- subject has role
- Sympatholytic
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
8 sectionsContents
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Society and culture
- Brand names
- References
- Further reading
Carteolol is a non-selective beta blocker used to treat glaucoma. It is administered in the form of eye drops.
Carteolol was patented in 1972 and approved for medical use in 1980.
Excerpted from Wikipedia’s “carteolol” article, available under the CC BY-SA 4.0 licence.