Structure via PubChem · Public domain (PubChem)
betaxolol
Sign in to saveAlso known as betaxolol HCl, Betoptic®, Kerlone®, SL-75212-10, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, Betaxololum, 1-(Isopropylamino)-3-[P-(cyclopropylmethoxyethyl)phenoxy]-2-propanol
Betaxolol is a beta blocker used in the treatment of hypertension and angina.
In the Vinony graph
Vinony's link graph records 811 inbound references to betaxolol, and connects out to adrenergic receptor, propranolol and glaucoma.
Vinony files it under Anxiolytics, Beta blockers and Cyclopropyl compounds.
Vinony links it to 23 Wikipedia language editions.
Key facts
- Drug.verifiedrevid
- 459977756
- Drug.image
- Betaxolol structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250px
- Drug.image2
- Betaxolol ball-and-stick.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Kerlone
- Drug.MedlinePlus
- a609023
- Drug.pregnancy_AU
- C
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- By mouth, ocular
- Drug.class
- Beta blocker; β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist
- Drug.ATC_prefix
- C07
- Drug.ATC_suffix
- AB05
- Drug.bioavailability
- 89%
- Drug.metabolism
- Liver
- Drug.elimination_half life
- 14–22 hours
- Drug.excretion
- Kidney (20%)
via Wikipedia infobox
Chemical data
- Formula
- C18H29NO3
- Molecular weight
- 307.4 g/mol
- IUPAC name
- 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
- SMILES
- CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
- InChIKey
- NWIUTZDMDHAVTP-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 50.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- oral, topical
- Indications
- cardiovascular disease, open-angle glaucoma, ocular hypertension, glaucoma
via ChEMBL · EBI
Research
1,053 papers- Betaxolol: A comprehensive profile.Profiles of drug substances, excipients, and related methodology · 2021
- Betaxolol.Australian and New Zealand journal of ophthalmology · 1989
- Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in hypertension.Drugs · 1986
- Ocular betaxolol. A review of its pharmacological properties, and therapeutic efficacy in glaucoma and ocular hypertension.Drugs · 1990
- Betaxolol in anxiety disorders.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists · 1998
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 307.214744
- Has use
- medication
Show 8 more facts
- Commons category
- Betaxolol
- chemical formula
- C₁₈H₂₉NO₃
- medical condition treated
- arterial hypertension
- canonical SMILES
- CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
- defined daily dose
- 20
- World Health Organisation international non-proprietary name
- betaxolol
- physically interacts with
- adrenoceptor beta 2
- significant drug interaction
- disopyramide
via Wikidata · CC0
~6 min read
Encyclopedic overview
15 sectionsContents
- Medical uses
- Hypertension
- Glaucoma
- Other uses
- Contraindications
- Side effects
- Pharmacology
- Pharmacodynamics
- Chemistry
- History
- Society and culture
- Brand names
- See also
- References
- External links
{{Infobox drug | verifiedrevid = 459977756 | image = Betaxolol structure.svg | image_class = skin-invert-image | width = 250px | image2 = Betaxolol ball-and-stick.png | image_class2 = bg-transparent | width2 =
| tradename = Kerlone | Drugs.com = | MedlinePlus = a609023 | pregnancy_AU = C | pregnancy_category = | legal_status = Rx-only | routes_of_administration = By mouth, ocular | class = Beta blocker; β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist | ATC_prefix = C07 | ATC_suffix = AB05 | ATC_supplemental =
Excerpted from Wikipedia’s “betaxolol” article, available under the CC BY-SA 4.0 licence.