Structure via PubChem · Public domain (PubChem)
betaxolol
Sign in to saveAlso known as betaxolol HCl, Betoptic®, Kerlone®, SL-75212-10, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, Betaxololum, 1-(Isopropylamino)-3-[P-(cyclopropylmethoxyethyl)phenoxy]-2-propanol
Betaxolol is a beta blocker used in the treatment of hypertension and angina.
Key facts
- Drug.verifiedrevid
- 459977756
- Drug.image
- Betaxolol structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250px
- Drug.image2
- Betaxolol ball-and-stick.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Kerlone
- Drug.MedlinePlus
- a609023
- Drug.pregnancy_AU
- C
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- By mouth, ocular
- Drug.class
- Beta blocker; β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist
- Drug.ATC_prefix
- C07
- Drug.ATC_suffix
- AB05
- Drug.bioavailability
- 89%
- Drug.metabolism
- Liver
- Drug.elimination_half life
- 14–22 hours
- Drug.excretion
- Kidney (20%)
via Wikipedia infobox
Chemical data
- Formula
- C18H29NO3
- Molecular weight
- 307.4 g/mol
- IUPAC name
- 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
- SMILES
- CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
- InChIKey
- NWIUTZDMDHAVTP-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 50.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- oral, topical
- Indications
- cardiovascular disease, open-angle glaucoma, ocular hypertension, glaucoma
via ChEMBL · EBI
Research
1,053 papers- Betaxolol: A comprehensive profile.Profiles of drug substances, excipients, and related methodology · 2021
- Betaxolol.Australian and New Zealand journal of ophthalmology · 1989
- Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in hypertension.Drugs · 1986
- Ocular betaxolol. A review of its pharmacological properties, and therapeutic efficacy in glaucoma and ocular hypertension.Drugs · 1990
- Betaxolol in anxiety disorders.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists · 1998
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 307.214744
- Has use
- medication
Show 8 more facts
- Commons category
- Betaxolol
- chemical formula
- C₁₈H₂₉NO₃
- medical condition treated
- arterial hypertension
- canonical SMILES
- CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
- defined daily dose
- 20
- World Health Organisation international non-proprietary name
- betaxolol
- physically interacts with
- adrenoceptor beta 2
- significant drug interaction
- disopyramide
via Wikidata · CC0
~6 min read
Encyclopedic overview
15 sectionsContents
- Medical uses
- Hypertension
- Glaucoma
- Other uses
- Contraindications
- Side effects
- Pharmacology
- Pharmacodynamics
- Chemistry
- History
- Society and culture
- Brand names
- See also
- References
- External links
{{Infobox drug | verifiedrevid = 459977756 | image = Betaxolol structure.svg | image_class = skin-invert-image | width = 250px | image2 = Betaxolol ball-and-stick.png | image_class2 = bg-transparent | width2 =
| tradename = Kerlone | Drugs.com = | MedlinePlus = a609023 | pregnancy_AU = C | pregnancy_category = | legal_status = Rx-only | routes_of_administration = By mouth, ocular | class = Beta blocker; β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist | ATC_prefix = C07 | ATC_suffix = AB05 | ATC_supplemental =
Excerpted from Wikipedia’s “betaxolol” article, available under the CC BY-SA 4.0 licence.