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milameline

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Milameline (CI-979, PD-129,409, RU-35,926) is a non-selective muscarinic acetylcholine receptor partial agonist with cognition-acting properties that was being investigated for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued.

Wikidata facts

Mass
154.110613
Show 4 more facts
chemical formula
C₈H₁₄N₂O
isomeric SMILES
CN1CCC=C(C1)/C=N/OC
canonical SMILES
CN1CCC=C(C1)C=NOC
Commons category
Milameline
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Encyclopedic overview

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Milameline (CI-979, PD-129,409, RU-35,926) is a non-selective muscarinic acetylcholine receptor partial agonist with cognition-acting properties that was being investigated for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued. Changing the O-methyl aldoxime to an O-propargyl oxime instead gives a separate molecule called RU 35986.

== See also == Alvameline Sabcomeline Tazomeline Xanomeline

Excerpted from Wikipedia’s “milameline” article, available under the CC BY-SA 4.0 licence.

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