Milameline (CI-979, PD-129,409, RU-35,926) is a non-selective muscarinic acetylcholine receptor partial agonist with cognition-acting properties that was being investigated for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued.
Milameline (CI-979, PD-129,409, RU-35,926) is a non-selective muscarinic acetylcholine receptor partial agonist with cognition-acting properties that was being investigated for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued. Changing the O-methyl aldoxime to an O-propargyl oxime instead gives a separate molecule called RU 35986.
== See also == Alvameline Sabcomeline Tazomeline Xanomeline
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).