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EntityQ6908807· pop 10· linked from 481 articles

Moperone (Luvatren, since discontinued) is a typical antipsychotic of the butyrophenone class which is marketed in Japan for the treatment of schizophrenia. It is an antagonist for the D2 (Ki 0.7–1.9 nM), D3 (Ki 0.1–1 nM), and 5-HT2A (Ki 52 nM) receptors. It also has a high binding affinity for the sigma receptors.

Wikidata facts

Mass
355.195
Show 4 more facts
canonical SMILES
CC1=CC=C(C=C1)C2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)O
chemical formula
C₂₂H₂₆FNO₂
Commons category
Moperone
defined daily dose
20
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Moperone (Luvatren, since discontinued) is a typical antipsychotic of the butyrophenone class which is marketed in Japan for the treatment of schizophrenia. It is an antagonist for the D2 (Ki 0.7–1.9 nM), D3 (Ki 0.1–1 nM), and 5-HT2A (Ki 52 nM) receptors. It also has a high binding affinity for the sigma receptors.

== References ==

Excerpted from Wikipedia’s “moperone” article, available under the CC BY-SA 4.0 licence.

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