naltrexone
Sign in to saveKey facts
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 464372546
- Drug.image
- Naltrexone_skeletal.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Naltrexone-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.tradename
- Revia, Vivitrol, Depade, others
- Drug.MedlinePlus
- a685041
- Drug.DailyMedID
- Naltrexone
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth, intramuscular, subcutaneous implant
- Drug.ATC_prefix
- N07
- Drug.ATC_suffix
- BB04
- Drug.legal_AU
- S4
- Drug.legal_BR
- C1
via Wikipedia infobox
Article
38 sectionsContents
- Medical uses
- Alcohol use disorder
- Opioid use disorder
- Others
- Available forms
- Contraindications
- Side effects
- Opioid withdrawal
- Adverse effects
- Liver damage
- Overdose
- Pharmacology
- Pharmacodynamics
- Opioid receptor blockade
- Other activities
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Pharmacogenetics
- Chemistry
- Analogues
- History
- Society and culture
- Generic names
- Brand names
- Controversies
- Research
- Depersonalization
- Low-dose naltrexone
- Self-injury
- Behavioral disorders
- Interferon alpha
- Critical addiction studies
- Sexual addiction
- Veterinary use
- References
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found effective in the treatment of other addictions and may be used for them off-label. It is taken orally or by injection into a muscle. Effects begin within 30 minutes, though a decreased desire for opioids may take a few weeks to occur.
Side effects may include trouble sleeping, anxiety, nausea, and headaches. In those still on opioids, opioid withdrawal may occur. Use is not recommended in people with liver failure. It is unclear if use is safe during pregnancy. Naltrexone is an opioid antagonist and works by blocking the effects of opioids, including both opioid drugs as well as opioids naturally produced in the brain.