NBQX
Sign in to saveNBQX (2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) is an antagonist of the AMPA receptor.
Chemical data
- Formula
- C12H8N4O6S
- Molecular weight
- 336.28 g/mol
- IUPAC name
- 6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +336.016455
Show 1 more fact
- P2868
- anxiolytic
via Wikidata · CC0
Article
2 sectionsContents
- See also
- References
NBQX (2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) is an antagonist of the AMPA receptor.
NBQX blocks AMPA receptors in micromolar concentrations (~10–20 μM) and also blocks kainate receptors. In experiments, it is used to counter glutamate excitotoxicity. NBQX was found to have anticonvulsant activity in rodent seizure models.