NEFM
Sign in to saveAlso known as NEF3, NF-M, NFM, neurofilament, medium polypeptide, neurofilament medium, neurofilament medium chain
Neurofilament medium polypeptide (NF-M) is a protein that in humans is encoded by the NEFM gene.
Gene data
NEFM- Name
- neurofilament medium chain
- Type
- protein-coding
- Aliases
- NEF3, NF-M, NFM
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
via MyGene.info
Gene · Ensembl
neurofilament medium chain
- Symbol
- NEFM
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:24,913,758-24,919,098
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 38041
- exact match
- identifiers.org/ncbigene/4741
- genomic end
- 24776607
- genomic start
- 24913758
- cytogenetic location
- 8p21.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Neurofilament medium polypeptide (NF-M) is a protein that in humans is encoded by the NEFM gene.
== Function ==