Structure via PubChem · Public domain (PubChem)
nitecapone
Sign in to saveNitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT). It was patented as an antiparkinson medication but was never marketed.
Chemical data
- Formula
- C12H11NO6
- Molecular weight
- 265.22 g/mol
- IUPAC name
- 3-[(3,4-dihydroxy-5-nitrophenyl)methylidene]pentane-2,4-dione
- SMILES
- CC(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C(=O)C
- InChIKey
- UPMRZALMHVUCIN-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 120 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 265.059
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₂H₁₁NO₆
- canonical SMILES
- CC(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C(=O)C
- subject has role
- antioxidant
- Commons category
- Nitecapone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT). It was patented as an antiparkinson medication but was never marketed.
==See also== List of investigational Parkinson's disease drugs Catechol-O-methyltransferase inhibitor
Excerpted from Wikipedia’s “nitecapone” article, available under the CC BY-SA 4.0 licence.