-Nitrendipin%20Structural%20Formula%20V1.svg)
nitrendipine
Sign in to saveNitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure and can reduce the cardiotoxicity of cocaine.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 408771000
- Drug.IUPAC_name
- (RS)-3-Ethyl 5-methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- Drug.image
- (RS)-Nitrendipin Structural Formula V1.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Skeletal formula of nitrendipine
- Drug.width
- 200
- Drug.image2
- Nitrendipine-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Ball-and-stick model of the nitrendipine molecule
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Baypress
- Drug.routes_of_administration
- By mouth
- Drug.bioavailability
- 60–70%
- Drug.protein_bound
- 98%
- Drug.metabolism
- Hepatic (completely)
- Drug.onset
- 1–2 hours
via Wikipedia infobox
Article
4 sectionsContents
- Medical uses
- Mechanism of action
- Stereochemistry
- References
Nitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure and can reduce the cardiotoxicity of cocaine.
It was patented in 1971 and approved for medical use in 1985.
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Categories
3-Nitrophenyl compoundsAntimineralocorticoidsCalcium channel blockersCarboxylate estersDihydropyridinesDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs with no legal statusECHA InfoCard ID from WikidataEthyl estersGlycine receptor antagonistsMethyl esters