Structure via PubChem · Public domain (PubChem)
norpipanone
Sign in to saveNorpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries. It had originally not been under international control but upon observation of case reports of addiction it was reviewed and shortly thereafter became a controlled substance. In the United States, it is a Schedule I controlled substance (ACSCN 9636, zero annual manufacturing quota as of 2014). The salts in use are the hydrobromide (free base conversion ratio 0.806) and hydrochloride (0.902).
Chemical data
- Formula
- C23H29NO
- Molecular weight
- 335.5 g/mol
- IUPAC name
- 4,4-diphenyl-6-piperidin-1-ylhexan-3-one
- SMILES
- CCC(=O)C(CCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3
- InChIKey
- WCDSHELZWCOTMI-UHFFFAOYSA-N
- XLogP
- 4.8
- Polar surface area
- 20.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 335.225
Show 2 more facts
- chemical formula
- C₂₃H₂₉NO
- canonical SMILES
- CCC(=O)C(CCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries. It had originally not been under international control but upon observation of case reports of addiction it was reviewed and shortly thereafter became a controlled substance. In the United States, it is a Schedule I controlled substance (ACSCN 9636, zero annual manufacturing quota as of 2014). The salts in use are the hydrobromide (free base conversion ratio 0.806) and hydrochloride (0.902).
==Synthesis== class=skin-invert-image|thumb|center|700px|Norpipanone synthesis:
Excerpted from Wikipedia’s “norpipanone” article, available under the CC BY-SA 4.0 licence.