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olprinone
Sign in to saveOlprinone (INN) is a cardiotonic agent. It has been marketed in Japan since 1996.
In the Vinony graph
Vinony's link graph records 97 inbound references to olprinone, and connects out to Japan, medication and circulatory system.
Vinony files it under 2-Pyridones, Antianginals and Chemical pages without DrugBank identifier.
Vinony links it to 4 Wikipedia language editions.
Chemical data
- Formula
- C14H10N4O
- Molecular weight
- 250.25 g/mol
- IUPAC name
- 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
- SMILES
- CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2
- InChIKey
- JPAWFIIYTJQOKW-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 70.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
188 papers- Olprinone: a phosphodiesterase III inhibitor with positive inotropic and vasodilator effects.Cardiovascular drug reviews · 2002
- Systematic review and meta-analysis of the efficacy of olprinone and MEFV gene in treating heart failure.Cellular and molecular biology (Noisy-le-Grand, France) · 2023
- Effect of olprinone on ischemia-reperfusion induced myocardial injury in rats.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2019
- The effects of olprinone, a phosphodiesterase 3 inhibitor, on systemic and cerebral circulation.Current vascular pharmacology · 2006
- [Research status of olprinone in cardiovascular diseases].Zhonghua wei zhong bing ji jiu yi xue · 2018
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 250.085
Show 4 more facts
- canonical SMILES
- CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2
- chemical formula
- C₁₄H₁₀N₄O
- subject has role
- cardiotonic
- Commons category
- Olprinone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Olprinone (INN) is a cardiotonic agent. It has been marketed in Japan since 1996.
==References==
Excerpted from Wikipedia’s “olprinone” article, available under the CC BY-SA 4.0 licence.
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Japan
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medication
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circulatory system
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intravenous infusion and defusion
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