ORC4
Sign in to saveAlso known as ORC4L, ORC4P, origin recognition complex subunit 4
Origin recognition complex subunit 4 is a protein that in humans is encoded by the ORC4 (ORC4L) gene.
In the Vinony graph
Within Vinony's link graph, ORC4 is referenced by 95 other articles, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 2.
Its subject is documented across 7 Wikipedia language editions.
Gene data
ORC4- Name
- origin recognition complex subunit 4
- Type
- protein-coding
- Position
- 147,930,396–148,021,784 (−)
- Aliases
- ORC4L, ORC4P
- Ensembl
- ENSG00000115947
- RefSeq RNA
- NM_001190879.3, NM_001190881.3, NM_001190882.3, NM_001374270.1, NM_001374272.1
- RefSeq protein
- NP_001177808.1, NP_001177810.1, NP_001177811.1, NP_001361199.1, NP_001361201.1
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. [provided by RefSeq, Oct 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
origin recognition complex subunit 4
- Symbol
- ORC4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:147,930,396-148,021,784
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8059
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5000
- genomic end
- 148779147
- genomic start
- 147930396
- chromosome
- human chromosome 2
- cytogenetic location
- 2q23.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Origin recognition complex subunit 4 is a protein that in humans is encoded by the ORC4 (ORC4L) gene.
== Function ==
Excerpted from Wikipedia’s “ORC4” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0