P2RY14

Also known as BPR105, GPR105, P2Y14, purinergic receptor P2Y14

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.

In the Vinony graph

Vinony's link graph records 485 inbound references to P2RY14, and connects out to adenosine receptor, PubMed and Ensembl genome database project.

Vinony files it under Genes on human chromosome 3 and G protein-coupled receptors.

Vinony links it to 5 Wikipedia language editions.

Gene data

P2RY14

Name: purinergic receptor P2Y14
Type: protein-coding
Position: 151,212,115–151,278,811 (−)
Aliases: BPR105, GPR105, P2Y14
Ensembl: ENSG00000174944
RefSeq RNA: NM_001081455.2, NM_014879.4, XM_005247922.4, XM_005247923.4, XM_011513340.4
RefSeq protein: NP_001074924.1, NP_055694.3, XP_005247979.1, XP_005247980.1, XP_011511642.1

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled purinergic nucleotide receptor signaling pathway

Molecular function

G protein-coupled receptor activity G protein-coupled purinergic nucleotide receptor activity G protein-coupled purinergic nucleotide receptor activity G protein-coupled UDP receptor activity

Cellular component

plasma membrane plasma membrane plasma membrane membrane membrane

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)Signal Transduction Signaling by GPCR Class A/1 (Rhodopsin-like receptors)GPCR downstream signalling P2Y receptors Nucleotide-like (purinergic) receptors G alpha (i) signalling events GPCR ligand binding GPCRs, Class A Rhodopsin-like

via MyGene.info

Gene · Ensembl

purinergic receptor P2Y14

Symbol: P2RY14
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:151,212,115-151,278,811
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 15769
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/9934
genomic end: 151278542
genomic start: 150929905
chromosome: human chromosome 3
cytogenetic location: 3q25.1
expressed in: visceral pleura

Sources (4)

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Encyclopedic overview

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Contents

See also
References
Further reading
External links

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.

Excerpted from Wikipedia’s “P2RY14” article, available under the CC BY-SA 4.0 licence.