PDCD4
Sign in to saveAlso known as H731, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death 4
Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21.
In the Vinony graph
Vinony's link graph records 12 inbound references to PDCD4, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 10.
Vinony links it to 6 Wikipedia language editions.
Gene data
PDCD4- Name
- programmed cell death 4
- Type
- protein-coding
- Position
- 110,871,790–110,900,013 (+)
- Aliases
- H731
- Ensembl
- ENSG00000150593
- RefSeq RNA
- NM_001199492.2, NM_014456.5, NM_145341.4
- RefSeq protein
- NP_001186421.1, NP_055271.2, NP_663314.1
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
programmed cell death 4
- Symbol
- PDCD4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:110,871,790-110,900,013
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PDCD4 PDB 2ggf.png
Show 7 more facts
- HomoloGene ID
- 7879
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/27250
- genomic end
- 112659764
- genomic start
- 112631565
- chromosome
- human chromosome 10
- cytogenetic location
- 10q25.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21.
== Function ==
Excerpted from Wikipedia’s “PDCD4” article, available under the CC BY-SA 4.0 licence.