PPARGC1B
Sign in to saveAlso known as ERRL1, PERC, PGC-1(beta), PGC1B, PPARG coactivator 1 beta
Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.
Gene data
PPARGC1B- Name
- PPARG coactivator 1 beta
- Type
- protein-coding
- Aliases
- ERRL1, PERC, PGC-1(beta), PGC1B
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 15776
- exact match
- identifiers.org/ncbigene/133522
- genomic end
- 149234585
- genomic start
- 149109861
- cytogenetic location
- 5q32
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Article
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Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.
==See also== PPARGC1A Peroxisome proliferator-activated receptor Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor delta Peroxisome proliferator-activated receptor gamma Transcription coregulator