蛋白質資料庫

October 2011 Molecule of the Month features historic structures that set the foundation for the PDB archive. In 2003, the Worldwide Protein Data Bank (wwPDB ) was formed to maintain a single PDB archive of macromolecular structural data that is freely and publicly available to the global community. It consists of organizations that act as deposition, data processing and distribution centers for PDB data. CARB/NIST left RCSB PDB in 2005 (see Emeritus RCSB PDB Leadership ). In 2021, RCSB PDB and the wwPDB celebrated the 50th Anniversary of the PDB with symposia, materials, and more. Nobel Prize in Chemistry: to David Baker for computational protein design and to Demis Hassabis and John M. Jumper for protein structure prediction Nobel Prize in Chemistry Carolyn Bertozzi, Morten Meldal, K. Barry Sharpless for the development of click chemistry and bioorthogonal chemistry Nobel Prize in Chemistry: Emmanuelle Charpentier and Jennifer A. Doudna for the development of a method for genome editing Nobel Prize awarded to Frances H. Arnold for the Directed Evolution of Enzymes Nobel Prize in Chemistry: Robert J. Lefkowitz and Brian K. Kobilka for studies of G-protein-coupled receptors Nobel Prize in Chemistry: Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath for studies of the structure and function of the ribosome Nobel Prize in Chemistry Roger D. Kornberg for his studies of the molecular basis of eukaryotic transcription Carter, A.P., Clemons, W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T. and Ramakrishnan, V. (2000) Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature , 407, 340-348. Nobel Prize in Chemistry: Paul D. Boyer and John E. Walker for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine