Structure via PubChem · Public domain (PubChem)
پروکسی فیلین
Sign in to saveProxyphylline is a xanthine derivative that acts as a cardiac stimulant, vasodilator and bronchodilator.
Chemical data
- Formula
- C10H14N4O3
- Molecular weight
- 238.24 g/mol
- IUPAC name
- 7-(2-hydroxypropyl)-1,3-dimethylpurine-2,6-dione
- SMILES
- CC(CN1C=NC2=C1C(=O)N(C(=O)N2C)C)O
- InChIKey
- KYHQZNGJUGFTGR-UHFFFAOYSA-N
- XLogP
- -0.8
- Polar surface area
- 78.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Airway obstruction
via ChEMBL · EBI
Research
93 papers- Antifungal polybrominated proxyphylline derivative induces Candida albicans calcineurin stress response in Galleria mellonella.Bioorganic & medicinal chemistry letters · 2020
- Biocatalytic hydrogen-transfer to access enantiomerically pure proxyphylline, xanthinol, and diprophylline.Bioorganic chemistry · 2022
- Investigation of the Binary System of Proxyphylline Enantiomers: Structural Resolution and Phase Diagram Determination.Molecular pharmaceutics · 2024
- Overadditive synergism between theophylline, diprophylline and proxyphylline in tracheal smooth muscle relaxation.Arzneimittel-Forschung · 1983
- Synthesis of novel proxyphylline derivatives with dual Anti-Candida albicans and anticancer activity.European journal of medicinal chemistry · 2018
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 238.107
Show 4 more facts
- canonical SMILES
- CC(CN1C=NC2=C1C(=O)N(C(=O)N2C)C)O
- chemical formula
- C₁₀H₁₄N₄O₃
- subject has role
- bronchodilator
- Commons category
- Proxyphylline
Sources (2)
via Wikidata · CC0
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via Wikidata sitelinks · CC0