RAD54B
Sign in to saveAlso known as RDH54, RAD54 homolog B (S. cerevisiae), RAD54 homolog B
DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.
Gene data
RAD54B- Name
- RAD54 homolog B
- Type
- protein-coding
- Aliases
- RDH54
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
RAD54 homolog B
- Symbol
- RAD54B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:94,371,960-94,475,134
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8240
- exact match
- identifiers.org/ncbigene/25788
- cytogenetic location
- 8q22.1
- genomic start
- 95384188
- genomic end
- 94475115
Sources (4)
via Wikidata · CC0
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Article
4 sectionsContents
- Interactions
- Cancer
- References
- Further reading
DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.