S100A11

Also known as HEL-S-43, MLN70, S100C, S100 calcium binding protein A11

S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene.

Gene data

S100A11

Name: S100 calcium binding protein A11
Type: protein-coding
Position: 152,032,504–152,047,907 (−)
Aliases: HEL-S-43, MLN70, S100C
Ensembl: ENSG00000163191
RefSeq RNA: NM_005620.2
RefSeq protein: NP_005611.1

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008].

Pathways

Innate Immune System Immune System Neutrophil degranulation

via MyGene.info

Gene · Ensembl

S100 calcium binding protein A11

Symbol: S100A11
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:152,032,504-152,047,907
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein S100A11 PDB 1V4Z.png

Show 5 more facts

HomoloGene ID: 55916
exact match: identifiers.org/ncbigene/6282
genomic end: 152020383
genomic start: 152004982
cytogenetic location: 1q21.3

Sources (4)

via Wikidata · CC0

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Article

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Contents

Function
S100A11 in pathologies
References
Further reading

S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene.

== Function == The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A11, also known as calgizzarin or 100C, is a small acidic protein. Along with all 13 members of the S100 family, are located as a cluster on chromosome 1q21. It was first found in 1989, and later isolated from chicken gizzard muscles.