RBL2
Sign in to saveAlso known as P130, Rb2, retinoblastoma-like 2, RB transcriptional corepressor like 2, BRUWAG
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, RBL2 is referenced by 830 other articles, and connects out to PubMed, homeobox and Ensembl genome database project.
Vinony files it under Genes on human chromosome 16 and Transcription factors.
Its subject is documented across 6 Wikipedia language editions.
Gene data
RBL2- Name
- RB transcriptional corepressor like 2
- Type
- protein-coding
- Position
- 53,433,977–53,491,668 (+)
- Aliases
- BRUWAG, P130, Rb2
- Ensembl
- ENSG00000103479
- RefSeq RNA
- NM_001323608.2, NM_001323609.2, NM_001323610.2, NM_001323611.1, NM_005611.4
- RefSeq protein
- NP_001310537.1, NP_001310538.1, NP_001310539.1, NP_001310540.1, NP_005602.3
Enables promoter-specific chromatin binding activity. Involved in regulation of lipid kinase activity. Acts upstream of or within negative regulation of gene expression. Located in chromosome; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RB transcriptional corepressor like 2
- Symbol
- RBL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:53,433,977-53,491,668
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Research
565 papers- The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms.Nature communications · 2024
- RBL2 Regulates Cardiac Sensitivity to Anthracycline Chemotherapy.JACC. CardioOncology · 2023
- Loss of Rbl2 (Retinoblastoma-Like 2) Exacerbates Myocardial Ischemia/Reperfusion Injury.Journal of the American Heart Association · 2022
- RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis.Cell death & disease · 2024
- RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling.Cell reports · 2023
via PubMed
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4098
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5934
- genomic end
- 53491648
- genomic start
- 53467889
- chromosome
- human chromosome 16
- cytogenetic location
- 16q12.2
Sources (4)
via Wikidata · CC0