Structure via PubChem · Public domain (PubChem)
Repaglinide
Sign in to saveAlso known as (-)-repaglinide, AGEE-623ZW, AG-EE 388 ZW, AG-EE 623 ZW
composto chimico
Chemical data
- Formula
- C27H36N2O4
- Molecular weight
- 452.6 g/mol
- IUPAC name
- 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
- SMILES
- CCOC1=C(C=CC(=C1)CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
- InChIKey
- FAEKWTJYAYMJKF-QHCPKHFHSA-N
- XLogP
- 5.2
- Polar surface area
- 78.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1997
- Admin. routes
- oral
- Indications
- diabetes mellitus, hypertension, atherosclerosis, Hypercholesterolemia
via ChEMBL · EBI
Research
1,006 papers- Repaglinide.Drugs & aging · 1998
- Repaglinide: prandial glucose regulation in clinical practice.Diabetes, obesity & metabolism · 2000
- Repaglinide: a review of its use in type 2 diabetes mellitus.Drugs · 2012
- Repaglinide, a new oral antidiabetic agent: a review of recent preclinical studies.European journal of clinical investigation · 1999
- Repaglinide as monotherapy in Type 2 diabetes.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 1999
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Mass
- 452.267508
- Has use
- medication
Show 8 more facts
- chemical formula
- C₂₇H₃₆N₂O₄
- defined daily dose
- 4
- World Health Organisation international non-proprietary name
- repaglinide
- isomeric SMILES
- CCOC1=C(C=CC(=C1)CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
- canonical SMILES
- CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
- Commons category
- Repaglinide
- subject has role
- anti-diabetic medication
- found in taxon
- Salvia regla
Sources (6)
via Wikidata · CC0
Article · Italiano
Repaglinide è un principio attivo farmaceutico, derivato dell'acido benzoico, che viene utilizzato come farmaco antidiabetico. Appartiene alla classe dei farmaci noti come glinidi o meglitinidi. Repaglinide è venduta in Italia dalla società farmaceutica Novo Nordisk A/S con il nome commerciale di Novonorm nella forma farmaceutica di compresse da 0,5mg, 1mg e 2mg. È inoltre commercializzata da numerose altre società farmaceutiche come medicinale equivalente.
Abstract from DBpedia / Wikipedia · CC BY-SA