Structure via PubChem · Public domain (PubChem)
reproterol
Sign in to saveReproterol is a short-acting β2 adrenoreceptor agonist used in the treatment of asthma.
Chemical data
- Formula
- C18H23N5O5
- Molecular weight
- 389.4 g/mol
- IUPAC name
- 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-1,3-dimethylpurine-2,6-dione
- SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCCNCC(C3=CC(=CC(=C3)O)O)O
- InChIKey
- WVLAAKXASPCBGT-UHFFFAOYSA-N
- XLogP
- -0.5
- Polar surface area
- 131 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Airway obstruction, asthma
via ChEMBL · EBI
Research
91 papers- Reproterol: beta-2-agonist, theophylline, or both?Respiration; international review of thoracic diseases · 1999
- Cromoglycate, reproterol, or both--what's best for exercise-induced asthma?Sleep & breathing = Schlaf & Atmung · 2012
- Inhibition by reproterol of cAMP PDE in intact mastocytoma P-815 cells.Pulmonary pharmacology & therapeutics · 2004
- Excretion study of the beta2-agonist reproterol in human urine.Journal of chromatography. B, Biomedical sciences and applications · 1999
- Reproterol--A monomolecular combination of orciprenaline and theophylline: novel aspects of its mode of action in asthma.Respiration; international review of thoracic diseases · 1999
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 389.17
Show 5 more facts
- chemical formula
- C₁₈H₂₃N₅O₅
- canonical SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCCNCC(C3=CC(=CC(=C3)O)O)O
- subject has role
- bronchodilator
- Commons category
- Reproterol
- physically interacts with
- adrenoceptor beta 2
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- Stereochemistry
- References
{{Infobox drug | Verifiedfields = changed | verifiedrevid = 448131419 | IUPAC_name = (RS)-7-(3-{[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino}propyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione | image = (RS)-Reproterol Structural Formula V1.svg | image_class = skin-invert-image | width = 250
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_DE = Rx only | legal_status = | routes_of_administration = Inhalation (MDI), IV
Excerpted from Wikipedia’s “reproterol” article, available under the CC BY-SA 4.0 licence.