S100A5

Also known as S100D, S100 calcium binding protein A5

S100 calcium-binding protein A5 (S100A5) is a protein that is encoded by the S100A5 gene in humans.

Gene data

S100A5

Name: S100 calcium binding protein A5
Type: protein-coding
Aliases: S100D

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

S100 calcium binding protein A5

Symbol: S100A5
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:153,537,147-153,543,074
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein S100A5 PDB 2KAX.png

Show 5 more facts

HomoloGene ID: 2224
exact match: identifiers.org/ncbigene/6276
genomic end: 153514241
genomic start: 153509623
cytogenetic location: 1q21.3

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S100 calcium-binding protein A5 (S100A5) is a protein that is encoded by the S100A5 gene in humans.

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes, such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain.