S100A5
Sign in to saveAlso known as S100D, S100 calcium binding protein A5
S100 calcium-binding protein A5 (S100A5) is a protein that is encoded by the S100A5 gene in humans.
In the Vinony graph
Within Vinony's link graph, S100A5 is referenced by 3 other articles, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 1 and S100 proteins.
Its subject is documented across 4 Wikipedia language editions.
Gene data
S100A5- Name
- S100 calcium binding protein A5
- Type
- protein-coding
- Position
- 153,537,147–153,543,074 (−)
- Aliases
- S100D
- Ensembl
- ENSG00000196420
- RefSeq RNA
- NM_001394232.1, NM_001394233.1, NM_001394234.1, NM_002962.2, XM_017002029.2
- RefSeq protein
- NP_001381161.1, NP_001381162.1, NP_001381163.1, NP_002953.2, XP_016857518.1
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
S100 calcium binding protein A5
- Symbol
- S100A5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:153,537,147-153,543,074
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein S100A5 PDB 2KAX.png
Show 7 more facts
- HomoloGene ID
- 2224
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6276
- genomic end
- 153514241
- genomic start
- 153509623
- chromosome
- human chromosome 1
- cytogenetic location
- 1q21.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
S100 calcium-binding protein A5 (S100A5) is a protein that is encoded by the S100A5 gene in humans.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes, such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain.
Excerpted from Wikipedia’s “S100A5” article, available under the CC BY-SA 4.0 licence.