solifenacin

Solifenacin, sold as the brand name Vesicare among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). It may help with incontinence, urinary frequency, and urinary urgency.

Chemical data

Formula: C23H26N2O2
Molecular weight: 362.5 g/mol
IUPAC name: [(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
SMILES: C1CN2CCC1[C@H](C2)OC(=O)N3CCC4=CC=CC=C4[C@@H]3C5=CC=CC=C5
InChIKey: FBOUYBDGKBSUES-VXKWHMMOSA-N
XLogP: 4
Polar surface area: 32.8 Å²
H-bond donors: 0
H-bond acceptors: 3
Formal charge: 0

via PubChem

~9 min read

Encyclopedic overview

13 sections

Contents

Medical use
Contraindications
Side effects
Interactions
Pharmacology
Mechanism of action
Pharmacokinetics
Chemistry
History
Society and culture
Cost
Footnotes
References

Benefits appear similar to other medications in the class. It is taken by mouth.

Excerpted from Wikipedia’s “solifenacin” article, available under the CC BY-SA 4.0 licence.

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