SUPT16H
Sign in to saveAlso known as CDC68, FACTP140, SPT16/CDC68, SPT16, SPT16 homolog, facilitates chromatin remodeling subunit, NEDDFAC
FACT complex subunit SPT16 is a protein that in humans is encoded by the SUPT16H gene.
In the Vinony graph
Within Vinony's link graph, SUPT16H is referenced by 3 other articles, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 14.
Its subject is documented across 6 Wikipedia language editions.
Gene data
SUPT16H- Name
- SPT16 homolog, facilitates chromatin remodeling subunit
- Type
- protein-coding
- Position
- 21,351,289–21,384,042 (−)
- Aliases
- CDC68, FACTP140, NEDDFAC, SPT16, SPT16/CDC68
- Ensembl
- ENSG00000092201
- RefSeq RNA
- NM_007192.4, XM_047430899.1, XM_054375309.1
- RefSeq protein
- NP_009123.1, XP_047286855.1, XP_054231284.1
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SPT16 homolog, facilitates chromatin remodeling subunit
- Symbol
- SUPT16H
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:21,351,289-21,384,042
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 5207
- genomic start
- 21351476
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/11198
- genomic end
- 21384019
- chromosome
- human chromosome 14
- cytogenetic location
- 14q11.2
- expressed in
- smooth muscle tissue
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
FACT complex subunit SPT16 is a protein that in humans is encoded by the SUPT16H gene.
== Function ==
Excerpted from Wikipedia’s “SUPT16H” article, available under the CC BY-SA 4.0 licence.