Structure via PubChem · Public domain (PubChem)
temocapril
Sign in to saveAlso known as Temocaprilum
Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US.
Chemical data
- Formula
- C23H28N2O5S2
- Molecular weight
- 476.6 g/mol
- IUPAC name
- 2-[(2S,6R)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid
- SMILES
- CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CS[C@@H](CN(C2=O)CC(=O)O)C3=CC=CS3
- InChIKey
- FIQOFIRCTOWDOW-BJLQDIEVSA-N
- XLogP
- 1
- Polar surface area
- 149 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 476.1439639959999
Show 5 more facts
- defined daily dose
- 10
- chemical formula
- C₂₃H₂₈N₂O₅S₂
- canonical SMILES
- CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(C2=O)CC(=O)O)C3=CC=CS3
- Commons category
- Temocapril
- isomeric SMILES
- CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CS[C@@H](CN(C2=O)CC(=O)O)C3=CC=CS3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US.
It is administered as inactive prodrug, then converted to its active metabolite, temocaprilat.
Excerpted from Wikipedia’s “temocapril” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0