tramazoline

Chemical data

Formula

C13H17N3

Molecular weight

215.29 g/mol

IUPAC name

N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine

SMILES

C1CCC2=C(C1)C=CC=C2NC3=NCCN3

InChIKey

QQJLHRRUATVHED-UHFFFAOYSA-N

XLogP

2

Polar surface area

36.4 Ų

H-bond donors

2

H-bond acceptors

1

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

Indications

Nasal congestion

via ChEMBL · EBI

• Tramazoline turns asymptomatic into symptomatic hyper-CK-emia.European journal of neurology · 2007
• Comparison of hemostatic effect and safety between epinephrine and tramazoline during nasotracheal intubation: a double-blind randomized trial.BMC anesthesiology · 2021
• The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients.The European respiratory journal · 2013
• Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial.Clinical and translational allergy · 2015
• [Decongesting effect of tramazoline on nasal airway patency and nasal symptoms as evaluated by acoustic rhinometry: an objective study in 30 allergic and six non-allergic subjects].Nihon Jibiinkoka Gakkai kaiho · 1998

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

215.142

via Wikidata · CC0