trihexyphenidyl
Sign in to saveTrihexyphenidyl (THP, benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease. It was approved by the FDA for the treatment of Parkinson's in the US in 1949.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 470614772
- Drug.IUPAC_name
- (RS)-1-Cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol
- Drug.image
- Trihexyphenidyl.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Trihexyphenidyl 3D.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Artane, Parkin, Pacitane, Hexymer
- Drug.MedlinePlus
- a682160
- Drug.DailyMedID
- Trihexyphenidyl
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- Oral
- Drug.ATC_prefix
- N04
- Drug.ATC_suffix
- AA01
- Drug.legal_AU
- S8
- Drug.legal_BR
- B1
- Drug.legal_US
- Rx-Only
- Drug.elimination_half life
- 3.3-4.1 hours
via Wikipedia infobox
Research
1,362 papers- Trihexyphenidyl dependence.Acta psychiatrica Scandinavica · 1984
- Trihexyphenidyl withdrawal encephalopathy.Annals of neurology · 1997
- Trihexyphenidyl and torticollis.Neurology · 1986
- Trihexyphenidyl abuse.The American journal of psychiatry · 1977
- Withdrawal of trihexyphenidyl.Acta psychiatrica Scandinavica · 1985
via PubMed
Article
14 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Stereochemistry
- History
- Society and culture
- Recreational use
- References
Trihexyphenidyl (THP, benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease. It was approved by the FDA for the treatment of Parkinson's in the US in 1949.
Trihexyphenidyl is a therapeutic alternative on the World Health Organization's List of Essential Medicines.