trimeprazine
Sign in to saveAlso known as methylpromazine, alimemazine, Panectyl
Alimemazine (INN), also known as trimeprazine, commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 477317349
- Drug.image
- Alimemazine.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Alimemazine Tartrate 10mg.jpg
- Drug.USAN
- trimeprazine
- Drug.BAN
- trimeprazine
- Drug.DailyMedID
- Trimeprazine
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth
- Drug.class
- Anti-allergic agent
- Drug.ATC_prefix
- R06
- Drug.ATC_suffix
- AD01
- Drug.legal_AU
- Schedule 4
- Drug.legal_AU_comment
- /Schedule 3; Schedule 2; Appendix K, clause 1
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.metabolism
- Liver
via Wikipedia infobox
Research
390 papers- Radioimmunoassay for trimeprazine in human plasma.Journal of pharmacological methods · 1984
- Pharmacokinetics of trimeprazine in children.Pharmacology & toxicology · 1990
- Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice.JCI insight · 2016
- Trimeprazine premedication in children.Anaesthesia · 1991
- Trimeprazine premedication in children.Anaesthesia · 1992
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- sulfur
- Mass
- 298.15037
- Has use
- medication
Show 8 more facts
- significant drug interaction
- loxapine
- chemical formula
- C₁₈H₂₂N₂S
- Commons category
- Alimemazine
- World Health Organisation international non-proprietary name
- alimemazine
- canonical SMILES
- CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)CN(C)C
- medical condition treated
- atopic dermatitis
- subject has role
- antipruritic
- defined daily dose
- 30
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Society and culture
- Brand names
- Use by Country
- Veterinary use
- References
Alimemazine (INN), also known as trimeprazine, commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness.
Despite being structurally related to the molecule chlorpromazine, it is not used as an antipsychotic.
Excerpted from Wikipedia’s “trimeprazine” article, available under the CC BY-SA 4.0 licence.