Structure via PubChem · Public domain (PubChem)
tropicamide
Sign in to saveAlso known as MYD947, Mydriacyl®, Tropicamida, Tropicamidum, Tropicamid
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with the examination of the eye. Specifically it is used to help examine the back of the eye. It is applied as eye drops. Effects occur within 40 minutes and last for up to a day.
Key facts
- Drug.PubChem
- 5593
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 409089198
- Drug.image
- Tropicamide.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Mydriacyl, others
- Drug.DailyMedID
- Tropicamide
- Drug.pregnancy_category
- C
- Drug.routes_of_administration
- Topical eye drops
- Drug.ATC_prefix
- S01
- Drug.ATC_suffix
- FA06
- Drug.legal_AU
- S4
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.protein_bound
- 45%
- Drug.CAS_number
- 1508-75-4
- Drug.IUPHAR_ligand
- 7319
via Wikipedia infobox
Chemical data
- Formula
- C17H20N2O2
- Molecular weight
- 284.35 g/mol
- IUPAC name
- N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
- SMILES
- CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2
- InChIKey
- BGDKAVGWHJFAGW-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 53.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
1,231 papers- Abuse of tropicamide eye drops: review of clinical data.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2022
- Tropicamide/Phenylephrine/Lidocaine Intracameral Injection: A Review in Cataract Surgery.Clinical drug investigation · 2019
- Comparison of cyclopentolate versus tropicamide cycloplegia: A systematic review and meta-analysis.Journal of optometry · 2018
- Injecting eye-drops: a mini-review on the non-clinical use of tropicamide.Human psychopharmacology · 2015
- Comparative efficacy of tropicamide 1% and cyclopentolate 1% for cycloplegic refraction: A systematic review and meta-analysis of randomized controlled trials.Optometry and vision science : official publication of the American Academy of Optometry · 2025
via PubMed
Wikidata facts
- Mass
- 284.152478
Show 4 more facts
- Commons category
- Tropicamide
- chemical formula
- C₁₇H₂₀N₂O₂
- World Health Organisation international non-proprietary name
- tropicamide
- canonical SMILES
- CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2
Sources (6)
via Wikidata · CC0
~5 min read
Article
8 sectionsContents
- Medical use
- Side effects
- Pharmacology
- Pharmacodynamics
- Recreational use
- Stereochemistry
- References
- External links
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with the examination of the eye. Specifically it is used to help examine the back of the eye. It is applied as eye drops. Effects occur within 40 minutes and last for up to a day.
Common side effects include blurry vision, increased intraocular pressure, and sensitivity to light. Another rare but severe side effect is psychosis, particularly in children. It is unclear if use during pregnancy is safe for the fetus. Tropicamide is in the antimuscarinic part of the anticholinergic family of medications. It works by making the muscles within the eye unable to respond to nerve signals.