Structure via PubChem · Public domain (PubChem)
xylazine
Sign in to saveAlso known as BAY-VA-1470, Bayer 1470, Xilazina, Xylazinum, Tranq, Zombie drug
Xylazine is a structural analog of clonidine and an α2-adrenergic receptor agonist, sold under many trade names worldwide, most notably the Bayer brand name Rompun, as well as Anased, Sedazine and Chanazine.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 1147600369
- Drug.IUPAC_name
- N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
- Drug.image
- Xylazine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 160
- Drug.image2
- Xylazine ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Rompun, Anased, Sedazine, Chanazine, others
- Drug.legal_AU
- S4
- Drug.legal_UK
- Class C
- Drug.legal_US
- Rx-only
- Drug.DailyMedID
- Xylazine
- Drug.legal_status
- Veterinary Use
- Drug.routes_of_administration
- By mouth, inhalation, subcutaneous, intramuscular, intravenous
- Drug.CAS_number
- 7361–61–7
- Drug.ATCvet
- yes
via Wikipedia infobox
Chemical data
- Formula
- C12H16N2S
- Molecular weight
- 220.34 g/mol
- IUPAC name
- N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
- SMILES
- CC1=C(C(=CC=C1)C)NC2=NCCCS2
- InChIKey
- BPICBUSOMSTKRF-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 49.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
4,331 papers- Xylazine poisoning: a systematic review.Clinical toxicology (Philadelphia, Pa.) · 2022
- Xylazine: A Drug Adulterant of Clinical Concern.Current pain and headache reports · 2024
- Xylazine Adulteration of the Heroin-Fentanyl Drug Supply : A Narrative Review.Annals of internal medicine · 2023
- Classics in Chemical Neuroscience: Xylazine.ACS chemical neuroscience · 2024
- Pharmacology and toxicology of xylazine: quid novum?European review for medical and pharmacological sciences · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- hydrogen
- Mass
- 220.10342
Show 5 more facts
- subject has role
- analgesic
- chemical formula
- C₁₂H₁₆N₂S
- canonical SMILES
- CC1=C(C(=CC=C1)C)NC2=NCCCS2
- route of administration
- subcutaneous injection
- Commons category
- Xylazine
via Wikidata · CC0
~18 min read
Encyclopedic overview
13 sectionsContents
- History
- Veterinary use
- Side-effects
- Pharmacokinetics
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics in humans
- Recreational use
- Side effects
- Overdose
- References
- Further reading
- External links
Xylazine is a structural analog of clonidine and an α2-adrenergic receptor agonist, sold under many trade names worldwide, most notably the Bayer brand name Rompun, as well as Anased, Sedazine and Chanazine.
Xylazine is a common veterinary drug used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other mammals. In veterinary anesthesia, it is often used in combination with ketamine. Veterinarians also use xylazine as an emetic, especially in cats. Drug interactions vary with different animals.
Excerpted from Wikipedia’s “xylazine” article, available under the CC BY-SA 4.0 licence.