Structure via PubChem · Public domain (PubChem)
zinterol
Sign in to saveZinterol is a beta-adrenergic agonist.
Chemical data
- Formula
- C19H26N2O4S
- Molecular weight
- 378.5 g/mol
- IUPAC name
- N-[2-hydroxy-5-[1-hydroxy-2-[(2-methyl-1-phenylpropan-2-yl)amino]ethyl]phenyl]methanesulfonamide
- SMILES
- CC(C)(CC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)NS(=O)(=O)C)O
- InChIKey
- XJBCFFLVLOPYBV-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 107 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
180 papers- Beta 2-adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium.Molecular and cellular biochemistry · 1996
- Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor.Naunyn-Schmiedeberg's archives of pharmacology · 2006
- Effects of the beta-2 adrenergic agonist zinterol on DRL behavior and locomotor activity.Psychopharmacology · 1993
- Murine ventricular L-type Ca(2+) current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor.British journal of pharmacology · 2001
- Effect of the beta-2 adrenergic agonist zinterol on norepinephrine turnover.Research communications in chemical pathology and pharmacology · 1993
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 378.161328
Show 4 more facts
- chemical formula
- C₁₉H₂₆N₂O₄S
- canonical SMILES
- CC(C)(CC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)NS(=O)(=O)C)O
- physically interacts with
- adrenoceptor beta 2
- Commons category
- Zinterol
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Zinterol is a beta-adrenergic agonist.
Its structure is based on soterenol (antiarrhythmic) and phentermine.
Excerpted from Wikipedia’s “zinterol” article, available under the CC BY-SA 4.0 licence.