ZNF384

Also known as CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1, zinc finger protein 384

Zinc finger protein 384 is a protein that in humans is encoded by the ZNF384 gene.

In the Vinony graph

Vinony's link graph records 816 inbound references to ZNF384, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.

It is catalogued under topics including Genes on human chromosome 12 and Transcription factors.

Vinony links it to 5 Wikipedia language editions.

Gene data

ZNF384

Name: zinc finger protein 384
Type: protein-coding
Aliases: CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011].

via MyGene.info