Structure via PubChem · Public domain (PubChem)
زوکلوپنتیکسول
Sign in to saveAlso known as cis(Z)-cloflupentixol, Cisordinol®, Clopixol®, NSC 64087, NSC169185, (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol, Zuclopenthixol, Zuclopenthixolum
Zuclopenthixol (brand names Cisordinol, Clopixol and others), also known as zuclopentixol, is a medication used to treat schizophrenia and other psychoses. It is classed, pharmacologically, as a typical antipsychotic. Chemically it is a thioxanthene. It is the cis-isomer of clopenthixol (Sordinol, Ciatyl). Clopenthixol was introduced in 1961, while zuclopenthixol was introduced in 1978.
Chemical data
- Formula
- C22H25ClN2OS
- Molecular weight
- 401 g/mol
- IUPAC name
- 2-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol
- SMILES
- C1CN(CCN1CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
- InChIKey
- WFPIAZLQTJBIFN-DVZOWYKESA-N
- XLogP
- 4.3
- Polar surface area
- 52 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- psychosis, anxiety, Dementia, depressive disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- clopenthixol
- Mass
- 400.137612
- Has use
- medication
Show 8 more facts
- chemical formula
- C₂₂H₂₅ClN₂OS
- canonical SMILES
- C1CN(CCN1CCC=C2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
- isomeric SMILES
- C1CN(CCN1CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
- World Health Organisation international non-proprietary name
- zuclopenthixol
- Commons category
- Zuclopenthixol
- defined daily dose
- 30
- significant drug interaction
- lithium
- safety classification and labelling
- Regulation (EC) No. 1272/2008
via Wikidata · CC0