Genes on human chromosome 19

protein-coding gene in the species Homo sapiens

Homer protein homolog 3 is a protein that in humans is encoded by the HOMER3 gene.

Leucine-rich alpha-2-glycoprotein 1 is a protein which in humans is encoded by the gene LRG1.

DNA-binding protein RFXANK is a protein that in humans is encoded by the RFXANK gene.

Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. In addition, tetherin has been designated as CD317 (cluster of differentiation 317). This protein is constitutively expressed in mature B cells, plasma cells and plasmacytoid dendritic cells, and in many other cells, it is only expressed as a response to stimuli from IFN pathway.

class of enzymes

Kallikrein-6 is a protein that in humans is encoded by the KLK6 gene. Kallikrein-6 is also referred to as neurosin, protease M, hK6, or zyme. It is a 223 amino acid sequence, derived from its 244 original form, which contains a 16 residue presignal and 5 residue activation peptide.

protein-coding gene in the species Homo sapiens

Transcription factor RelB is a protein that in humans is encoded by the RELB gene.

AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage as part of the insulin signal transduction pathway.

Endothelial zinc finger protein induced by tumor necrosis factor alpha is a protein that in humans is encoded by the ZNF71 gene.

RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene.

FK506-binding protein 8 is a protein that in humans is encoded by the FKBP8 gene.

Keratinocyte differentiation-associated protein is a protein that in humans is encoded by the KRTDAP gene.

Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Calcyphosin is a protein that in humans is encoded by the CAPS gene.

TCF3 fusion partner is a protein that in humans is encoded by the TFPT gene.

Numb-like protein is a protein that in humans is encoded by the NUMBL gene.

Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene.

protein-coding gene in the species Homo sapiens

Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms have been identified for this gene.

Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene.

Zinc finger protein OZF is a protein that in humans is encoded by the ZNF146 gene.

BRCA1-A complex subunit MERIT40 is a protein that in humans is encoded by the BABAM1 gene.

protein-coding gene in the species Homo sapiens

Vomeronasal type-1 receptor 2 is a protein that in humans is encoded by the VN1R2 gene.

Glutamate [NMDA] receptor subunit 3B is a protein that in humans is encoded by the GRIN3B gene.

protein-coding gene in the species Homo sapiens

Krueppel-related zinc finger protein 1 is a protein that in humans is encoded by the HKR1 gene.

Coiled-coil and C2 domain-containing protein 1A is a protein that in humans is encoded by the CC2D1A gene.

Potassium channel tetramerisation domain containing 15 also known as BTB/POZ domain-containing protein KCTD15 is protein that in humans is encoded by the KCTD15 gene.

Leukocyte immunoglobulin-like receptor subfamily B member 1 is a protein that in humans is encoded by the LILRB1 gene.

Unconventional prefoldin RPB5 interactor, also called URI1, is a protein that in humans is encoded by the URI1 gene.

Kin of IRRE-like protein 2, also known as NEPH3, is a protein that in humans is encoded by the KIRREL2 gene. It is primarily expressed in β cells of the pancreatic islets.

protein-coding gene in the species Homo sapiens

PSENEN, formally PEN-2 (presenilin enhancer 2), is a protein that is a regulatory component of the gamma secretase complex, a protease complex responsible for proteolysis of transmembrane proteins such as the Notch protein and amyloid precursor protein (APP). The gamma secretase complex consists of PEN-2, APH-1, nicastrin, and the catalytic subunit presenilin. PEN-2 is a 101-amino acid integral membrane protein likely with a topology such that both the N-terminus and the C-terminus face first the lumen of the endoplasmic reticulum and later the extracellular environment. Biochemical studies ha

Microtubule-associated protein 1S is a protein that in humans is encoded by the MAP1S gene.

Amyloid precursor like protein 1, also known as APLP1, is a protein encoded by the APLP1 gene in humans. APLP1 along with APLP2 are important modulators of glucose and insulin homeostasis.

protein-coding gene in the species Homo sapiens

GIPC PDZ domain containing family, member 1 (GIPC1) is a protein that in humans is encoded by the GIPC1 gene. GIPC was originally identified as it binds specifically to the C terminus of RGS-GAIP, a protein involved in the regulation of G protein signaling. GIPC is an acronym for "GAIP Interacting Protein C-terminus". RGS proteins are "Regulators of G protein Signaling" and RGS-GAIP is a "GTPase Activator protein for Gαi/Gαq", which are two major subtypes of Gα proteins. The human GIPC1 molecule is 333 amino acids or about 36 kDa in molecular size and consists of a central PDZ domain, a c

NLRP8, short for NOD-like receptor family pyrin domain containing 8, is an intracellular protein that is expressed in the ovaries, testes, and preimplantation embryos of mammals. It is also known as NALP8, NOD16, PAN4, and CLR19.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.

Spectrin, beta, non-erythrocytic 4, also known as SPTBN4, is a protein that in humans is encoded by the SPTBN4 gene.

SERTA domain-containing protein 1 is a protein that in humans is encoded by the SERTAD1 gene.

The human ATG4D gene encodes the protein Autophagy related 4D, cysteine peptidase.

Egl nine homolog 2 is a protein that in humans is encoded by the EGLN2 gene. ELGN2 is an alpha-ketoglutarate-dependent hydroxylase, a superfamily of non-haem iron-containing proteins.

Proto-oncogene vav is a protein that in humans is encoded by the VAV1 gene.

Pregnancy-specific beta-1-glycoprotein 3 is a protein that in humans is encoded by the PSG3 gene.

Protein Hook homolog 2 (HK2) is a protein that in humans is encoded by the HOOK2 gene.

Sodium channel subunit beta-1 is a protein that in humans is encoded by the SCN1B gene.

AP-3 complex subunit delta-1 is a protein that in humans is encoded by the AP3D1 gene.

'Unc-13 homolog A (C. elegans)' is a protein that in humans is encoded by the UNC13A gene and in mice by the Munc13-1 gene.

protein-coding gene in the species Homo sapiens

Radial spoke head protein 6 homolog A (RSPH6A) also known as radial spoke head-like protein 1 (RSHL1) is a protein that in humans is encoded by the RSPH6A gene.

Natural killer cell granule protein 7 (NKG7 protein) is a protein that in humans is encoded by the NKG7 gene. The protein is under study regarding potential in cancer research into T cell activity. A role of the NKG7 protein in regulating cell resistance and fighting tumors in certain types of cancer is being studied because of its ability to recognize and kill cancer cells through CD8+ T cell resilience that is essential for anti-tumor activity. The research suggests that the NKG7 protein allows the CD8+ T cells to continue killing malignant cells in certain circumstances and may prevent gro

Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen (CEA) gene family..

EGF-like module-containing mucin-like hormone receptor-like 3 is a protein encoded by the ADGRE3 gene. EMR3 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Retinol dehydrogenase 13 (all-trans/9-cis) is a protein that in humans is encoded by the RDH13 gene. This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described.

Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene.

Zinc finger protein 383 is a protein that in humans is encoded by the ZNF383 gene.

protein-coding gene in the species Homo sapiens