Human proteins

protein-coding gene in the species Homo sapiens

mTOR Complex 2 (mTORC2) is an acutely rapamycin-insensitive protein complex formed by serine/threonine kinase mTOR that regulates cell proliferation and survival, cell migration and cytoskeletal remodeling. The complex itself is rather large, consisting of seven protein subunits. The catalytic mTOR subunit, DEP domain containing mTOR-interacting protein (DEPTOR), mammalian lethal with sec-13 protein 8 (mLST8, also known as GβL), and TTI1/TEL2 complex are shared by both mTORC2 and mTORC1. Rapamycin-insensitive companion of mTOR (RICTOR), mammalian stress-activated protein kinase interacting pro

Kinesin-like protein KIF1C is a protein that in humans is encoded by the KIF1C gene. Kif1C is a fast, plus-end directed microtubule motor. It takes processive 8nm steps along microtubules and can generate forces of up to 5 pN. Kif1C transports α5β1-integrins in human cells. Kif1C has been shown to be non-essential in mouse with other proteins able to perform the same function. However, mutations in KIF1C lead to spastic paraplegia and cerebellar dysfunction in humans. These mutations usually result in a total loss of the protein or (partial) loss of function, such as significant lower force ou

protein-coding gene in the species Homo sapiens

Tonsoku-like, DNA repair protein is a protein that in humans is encoded by the TONSL gene.

Solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 is a protein in humans that is encoded by the SLC25A16 gene.

Mothers against decapentaplegic homolog 1 also known as SMAD family member 1 or SMAD1 is a protein that in humans is encoded by the SMAD1 gene.

protein-coding gene in the species Homo sapiens

Adaptin ear-binding coat-associated protein 2 is a protein that in humans is encoded by the NECAP2 gene.

Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2), also known as QCR2, UQCR2, or MC3DN5 is a protein that in humans is encoded by the UQCRC2 gene. The product of UQCRC2 is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b) and ten nuclear genes: UQCRC1, UQCRC2, Cytochrome c1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", a

SID1 transmembrane family member 2 is a protein that in humans is encoded by the SIDT2 gene.

Condensin complex subunit 2 also known as chromosome-associated protein H (CAP-H) or non-SMC condensin I complex subunit H (NCAPH) is a protein that in humans is encoded by the NCAPH gene. CAP-H is a subunit of condensin I, a large protein complex involved in chromosome condensation. Abnormal expression of NCAPH may be linked to various types of carcinogenesis as a prognostic indicator.

Hyaluronan and proteoglycan link protein 2 (HAPLN2) also known as brain link protein 1 (BRAL1) is a protein that in humans is encoded by the HAPLN2 gene. HAPLN1 codes for a related link protein that is expressed in cartilage while Bral1 is expressed in brain.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 is a protein that in humans is encoded by the WFIKKN2 gene.

Dynein, axonemal, heavy chain 7 is a protein in humans that is encoded by the DNAH7 gene.

Post-GPI attachment to proteins 1 is a protein that in humans is encoded by the PGAP1 gene.

Neuronal growth regulator 1 also known as NEGR1 is a protein which in humans is encoded by the NEGR1 gene.

Small G protein signaling modulator 2 is a protein that in humans is encoded by the SGSM2 gene.

SMAD family member 6, also known as SMAD6, is a protein that in humans is encoded by the SMAD6 gene.

Dolichol phosphate-mannose biosynthesis regulatory protein is a protein that in humans is encoded by the DPM2 gene.

RAB7, member RAS oncogene family-like 1 is a protein that in humans is encoded by the RAB7L1 gene. The gene is also known as RAB7L. RAB7L1 encodes a small GTP-binding protein and is a member of the Ras superfamily.

HFM1 is a gene that in humans encodes a protein necessary for homologous recombination of chromosomes. Biallelic mutations in HFM1 cause recessive primary ovarian insufficiency.

Kinesin family member 5B (KIF5B) is a protein that in humans is encoded by the KIF5B gene. It is part of the kinesin family of motor proteins.

'Unc-13 homolog A (C. elegans)' is a protein that in humans is encoded by the UNC13A gene and in mice by the Munc13-1 gene.

The human ATG4D gene encodes the protein Autophagy related 4D, cysteine peptidase.

Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene.

(See also: List of proteins in the human body)

Suppressor of cytokine signaling 4 is a protein that in humans is encoded by the SOCS4 gene.

Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene.

Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SMAD5 gene.

Chromosome 6 open reading frame 201, C6orf201, is a protein that in humans is encoded by the C6orf201 gene. In humans this gene encodes for a nuclear protein that is primarily expressed in the testis.

Protein NDRG4 is a protein that in humans is encoded by the NDRG4 gene.

CARMIL1 is a protein that in humans is encoded by the CARMIL1 gene. The gene is also known as LRRC16, LRRC16A, CARMIL, or CARMIL1a.

NGFI-A-binding protein 1 is a protein that in humans is encoded by the NAB1 gene.

mammalian protein found in Homo sapiens

Actin-like protein 7A is a protein that in humans is encoded by the ACTL7A gene.

Maltase-glucoamylase, intestinal is an enzyme that in humans is encoded by the MGAM gene.

Natural cytotoxicity triggering receptor 3 is a protein that in humans is encoded by the NCR3 gene. NCR3 has also been designated as CD337 (cluster of differentiation 337) and as NKp30. NCR3 belongs to the family of NCR membrane receptors together with NCR1 (NKp46) and NCR2 (NKp44).

Nck-associated protein 1 is a protein that in humans is encoded by the NCKAP1 gene.

Fanconi anemia group J protein (FANCJ) is a protein that in humans is encoded by the BRCA1-interacting protein 1 (BRIP1) gene. The protein is a 5'-3' DNA helicase (EC: 5.2.6.3) and ATPase that repairs interstrand crosslinks (ICLs), double-stranded breaks (DSBs) and guanine quadruplexes (G4) through the Fanconi anemia (FA) pathway. Damage or depletion of BRIP1 has been associated with various cancers as well as Fanconi anemia.

Neurogenic differentiation factor 2 is a protein that in humans is encoded by the NEUROD2 gene.

N-alpha-acetyltransferase 15, NatA auxiliary subunit also known as gastric cancer antigen Ga19 (GA19), NMDA receptor-regulated protein 1 (NARG1), and Tbdn100 is a protein that in humans is encoded by the NAA15 gene. NARG1 is the auxiliary subunit of the NatA (Nα-acetyltransferase A) complex. This NatA complex can associate with the ribosome and catalyzes the transfer of an acetyl group to the Nα-terminal amino group of proteins as they emerge from the exit tunnel.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 is a protein that in humans is encoded by the NDUFA2 gene. The NDUFA2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Mutations in the NDUFA2 gene are associated with Leigh's syndrome.

Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene.

Protein NDRG2 is a protein that in humans is encoded by the NDRG2 gene (NMYC downstream-regulated gene 2).

protein-coding gene in the species Homo sapiens

Neuralized-like protein 2 is a protein that in humans is encoded by the NEURL2 gene.

Melanotransferrin is a protein that in humans is encoded by the MFI2 gene. MFI2 has also recently been designated CD228 (cluster of differentiation 228).